· Defending Rolex 24 champion Action Express Racing ran into trouble shortly before the nine-hour mark when Joao Barbosa stopped on-track with no fuel pressure in the No. 5 Mustang Sampling Corvette DP. The car required a tow to the garage and returned to the track three laps down. At the end of the second segment, co-driver Christian Fittipaldi had moved to sixth, two laps down.
· Another Prototype contender ran into trouble early in the second Patrón Endurance Cup segment when Tony Kanaan drove the No. 02 Chip Ganassi Racing Ford EcoBoost/Riley to the garage for a splitter change. The team was able to make the repair under a yellow flag losing only one lap. Kanaan then got the car back onto the lead lap and Kyle Larson drove to the second spot at the end of the 12-hour mark.
· Leading into the 10th hour in the GTLM class, Pierre Kaffer pitted the No. 62 Risi Competizione Ferrari F458 Italia with a loss of horsepower. After multiple pit stops to diagnose the issue, Kaffer drove to the garage for repairs and the team later retired from the race reporting an electrical misfire.
· A multi-car incident involving the two Porsche North America Porsche 911 RSRs brought out the yellow flag in the 11th hour of the race. Both cars were running in the top five at the time of the collision, but sent the No. 912 of Earl Bamber to pit road and the No. 911 of Marc Lieb to the paddock for repairs.